![]() In treatment, while corticosteroids are the first line, immunosuppressive treatments can be applied in refractory cases. Clinical follow-up and treatment modalities for neurosarcoidosis remain unclear because the disease is rare early treatment is reported as important in terms of mortality and morbidity. Diagnosis can be accurate by detecting histopathological non-caseified granulomas associated with clinical and radiological symptoms. Diagnosis remains difficulties as there are no specific clinical and/or radiological symptoms of neurosarcoidosis (NS), mainly in patients without systemic manifestations. Various symptoms, such as encephalopathy, seizures, myelopathy, meningeal syndrome, and cerebellar involvement, may be presented ( 2). Central nervous system (CNS) involvement of sarcoidosis may affect the cranial nerves (52%), particularly the facial nerve, meninges, brain parenchyma, and hypothalamus. ![]() Nervous system involvement is observed in 5%–15% cases in 70% cases, neurological symptoms occur within the first 2 years of the systemic disease onset ( 1). ![]() Sarcoidosis is an inflammatory, multisystemic disease that can affect many organs, such as the lungs, lymph nodes, skin, and eyes.
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